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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2017ae7e2e6fd5d826c280000d61f85486f385595216ca377d9d976646abbe1' 
  AND token = 'wvzhfRvdU3ry6rwLg5LnRgToQ3e8GByg7j5OS2ElFLo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}