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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2d8bf481a2aa9478f298c8f44c043652c76d7d39370b98624142e3b541cdb55' 
  AND token = 'qY9O0cg0QN12o1+SR9ggA6lRvFCYmW3qMbCIsoQfTC4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}