SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01e0370cd0b4f5aee4d879bbee8e991c889167893234aad86c0ed55f3f188776' 
  AND token = 'gfqqLa1jHDYFbTEgOwJGAQmtuBess+ZJgzTJv/2ZN0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}