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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '371d5cc7e148b0e42803538daa91b60edeff316805c3989476184a1e656cdf2a' 
  AND token = 'iIMptqI4xrcIiHCd4gW38+gGEAd96471xlrJ3eX2Pco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}