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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14f664bc7b920e4abb8ab44072264601c53fbbaa8d9d82a35370666ebd0df1b9' 
  AND token = 'fN/4bsal/IWFSCXYJMU6ng9ecB7UN0I1JJOFdZDhslU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}