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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '495b2079aa3c083874fb31e573fedd6a211aab05afcbc2d3c3ead9c75d43cca6' 
  AND token = 'bARdsd5haNAb/hRIpv91XLZMOOTTuOCi+7Y4Pfl/ne4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}