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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90ad9ec56018132993f1e85aa9682699c3812a19760c148c0493bb54eff0ce4f' 
  AND token = 'v2YAjCOOIT1wGLIwx68TjkvyDAbW7Z6DxkxxFI725Kg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}