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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca43bc466fc5644e3725d1d66ebc0e1ecf78b300f6f6d5e68a8e8c676f65f8f3' 
  AND token = 'ksJY+FNYlfox1/k54izrxJ0PeLNo9e1oiz7r5gBlme4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}