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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '549d895a8dc5dbb38eb8288e48fc9438583af8b9010d6e2751e8b8e052315fc6' 
  AND token = 'liXGldMV23+RqnrHiVh73B/vdBOTmvXHstDO018L6hQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}