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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '220261fd6d8c628ed17ed81d5a19386f7a84d7ae7447a1d74e6886fa1076a05b' 
  AND token = 'F98vJZl4XCUzoAp6dPG1QQNkCwyctDt9Uz+GRYudYGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}