SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d4b9f1bb92fd1ea0b051d3f8c93170d696560e40a6aeb3a25520591eeae50c7' 
  AND token = 'wuC/+jQi/PaF4nqLTU9W1FKVb/6oG3qF9QfhlT5LJs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}