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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a81020f27f5190a4f8850dd1178bac461f2dfe7e6687456eabe6a6dd3995702' 
  AND token = 'r9jko9EVH7r0IMEcQhaIGvvq7QsxR7om2T4SHs0dLQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}