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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4e152c809db2b4e3c3f353b37392db37436f3617c081e18d3a4da7593adcb13' 
  AND token = 'e+zMGdNY/eARS0bMtAZUqpKsE9DLRGKW9mxz+K2sS7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}