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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ee9ee50d1d1f6f4c46d141693c8ba01268d10d0e9328a5c99ddf54aab68d186' 
  AND token = 'ExNKirYkj4V8vmGZKpxeesq4kyT9HLcJTnGQPOFuOBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}