SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a356f069b4f24ce8cff08535a8c3f4ef5885d74a227acd8a2e43e6990f4b1e4' 
  AND token = 'Poa5l6lgdHFlzOJWNUPc/FxkhMdCbbTbPWO/QIfhJzU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}