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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05b5a5edb04b2ad464fb265322b727356aa0486e108984f6a0eac11703a90b56' 
  AND token = 'OJ8Qp2Tm+rWYLohEFtI2tVbXEbEE6DdTlwADD9A69Uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}