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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de1a7b08315484d314976a73b35f2385fe45dd3e35241965ab5114c85f07df90' 
  AND token = 'uZaFQQmuzlIY+7difNtn/lNKU6CdTTcZ549wqiOTd1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}