SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80aac9649390eb47a0fab163e4427c38b5a931be5c900cd87333d063ec099b08' 
  AND token = 'nezm6NGHxsmG2qPjZQC5JbHa+2Pu3H2yMhhYez4MV3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}