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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8d1b24121ffca10105bd44d1fd4adc7a7eb9b507508e8c9a4240c7d5f15e9ba' 
  AND token = '4taHXsqbgYEBSS0qhxNBFpJx6IJTBy2V1ONkQupHnqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}