SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0a66b04ad4842defefa2a15e8713127e5455878f335431a1b642557e7223e94' 
  AND token = 'Fvby5KM0juJBTwudP2nvxATFMy+qZDbEQ8KvZBuk46Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}