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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a259de5b30a21d2170cb7d91c789a71a470140a086bf04aa66a03b2193fc4f50' 
  AND token = '1b5gO09YzfcjOfRDZfSoxCmDKFku8ZXCF754Ri6ppSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}