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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccb5a07a32afc0b16a576dd8c262b7822147261295d6a8b49b924f9ac5508745' 
  AND token = 'u+f3lCoaetcByEkx3DmNnJ7Ol29HZ57h64CwBak12vI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}