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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b0ab00fec6bdc0da952a0bf23d935b6f04913107df92f6b3f114390eec70ef5' 
  AND token = 'PrXMGAXeL7DAU5k8w3z9U2T92gWsqwOVVdKwWZxwcE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}