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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8b15205c41657a2b82765cec758912e59c3af15c09899754966b858115985d0' 
  AND token = 'O5p729vNh8Dl93zRtIzpC4iFCg6/k/G2AyTUrX0qOLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}