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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb4c2cb9abc318b6bed808671492a9356aa9cc025af853414196013087da3f3' 
  AND token = '5GUyGjNwNZ5OCGBnsMbtIVq5IQ1JstgMGrLxUeZqxbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}