SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caae351ac3ec7b945036c92e637c33429f8227c8a541939cca774d95b0942628' 
  AND token = 'JPaW+k4+pOLbjVD0b8vGvkXetf0OfBlzL6X/FS/4Wa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}