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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99b0fd3e3df994461eca02349c602891d07d317c39be396c84017df27baba00b' 
  AND token = 'VoIqn5Ofr9qloBMfNisiPTs6+xH23uzNLeZPMuZc8ug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00067

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}