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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fd5252aa1b163f2e1e51b6ee2ca562b59d70c23ab10c1dfa66c9bd289cd4f9c' 
  AND token = 'FcL26sq6rS3ZjzW6e6UHxieXln9kv7ZaXZqvocXNCTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}