SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f739cf747fc4e296887f18e7d68ad416bb9ea9d110d7a80a754161c40403064a' 
  AND token = 'E27OlqrUBE89A+zySo0sSM3zIMUUsrd1S0lgRZXLxBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}