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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7aa0d6c1ad69ee582f024346d4e9817c4942edc33f124ad14902a7caf1e01140' 
  AND token = 'fRzpn+XTuMribHbCXOuxgC9uR+h9afSVoBmFaF0JJag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}