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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0421e57fec950fdecb16e25528306bdb8ab43e93ca7c1d28fa2f95c582cf84bf' 
  AND token = 'yltFh3PUO5UdmTYl7iJJB+uOSuY037Cd4klGbffFk/A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}