SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '91f568c26eac78940a6361e718f3941029ea664de6172b53be8fe1976e9cfc7d' 
  AND token = 'df2efqxjUCHnPb3vyC/MUYES1CQSZwCbjSl528WSKpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}