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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b49a3a45051ec88e47fc44836f9396bccb9e62321464695f74fe25c9f87fd74' 
  AND token = 'OATizC+X0TC/6Hxyx5DlBXNl0u9uObjM0YuZwtjBn3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}