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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '686c20fea9f085e73cfda681b1d446aa4f2805e94a61797e2efcab55b683a8f9' 
  AND token = 'dS60ldWHmD+vYEeeggfn//aha1xtjzeT5ERW3UG9IgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}