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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd2d77b84cce5a1bb0a07f9468e21be29cb288a8da48ba238a3a70b6188f0166' 
  AND token = 'A9N5p/923K6RkkNoMKx1qYaazPkdYuovTm+RkOM2swg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}