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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c74c6c07a5ed9730a3f5f2cd2a4f6f0eeb8b289ff30adf8329e97c5aec51553' 
  AND token = 'IA5B2D1anl02KSqEspBy6Me8SMMQjPmhS1W/SKEeuzY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}