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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0aeb2bccb3c5f64d53eb22d3e8e790e871ddbd0ba21a522a54b8181d1842063a' 
  AND token = '+azGu3ul0Qg1kg2rO0F3Jo2S2GLEJFAKNTiKMumnPi8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}