SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a25c38a14194ef77844c57148ea9fa020d14a8ce24fc19a0d05c09e21f0d924' 
  AND token = 'FCxog6i2scH71u72iB6oshVY2KlaCe8JTRreNCU/bo4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}