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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbc157d886b0122ad4e52d5caccf9b7f9da022e4c7fe652a5e6a72f73f567a03' 
  AND token = '/fsKHSyGyVrDlpTOi8MyvMCSea5RqDPTflwJQR/jNj0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}