SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '106d8252b54230481fce1d931a545679a6629b8f4b74272a2097d27a5596c737' 
  AND token = 'uE6G98vUKHPV5eEgtTD45TKbEZAn+uuYfCu2DJYfVkE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}