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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43fd6016abcc292206c8f8ca5ce3a15529cf24bef2207a9f3a06ef61d8033a1c' 
  AND token = 'olMZm1Ubpfj8XYJfd7Rqdm4EQ8hxT8RdmcuiRLpmcxQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}