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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5e891971fbd1531de81056b421d69fe433258d1d239d2a64a0b9af28eb83447' 
  AND token = 'V1xW0HmbnCcW5kkBzqvbG93J/BIlkkJCvORHS5HNrxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}