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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbe188778a31f0f944b6238ad5b129ae5adb704aface10d48a852a5b39307054' 
  AND token = 'fdyJ3hDGs4rdRdwb9BtqZ6SsaN9+BBr52heG4ZhlJAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}