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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cb53afec5b3f5fb65370421633ea94a13c46f1e4850c687614f81fe7cba5999' 
  AND token = '5xiRTahicxTLeZrzf4x31G9/3ta/I4PKq1E2AxFVspg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}