SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b549389966cfe9dfc6d7386cb09e97817d33116711d15bcac6e4d5a3eab7f1a2' 
  AND token = 'y1Shosyz1oT621tRmZ5W/CAVy0jtWt/Tx0gyjCQa1zY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}