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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b914d07e4f7d3f77f472d74b8a1969b83a9b2adde884fee3e2c760f23b11e14' 
  AND token = 'vgBpUcekzk9+udQT5Qs0mqAt3hvxqKbbRBg0eA6XB5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}