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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bbe1b492089f44a5a3bd4c2205ee5241a9d1373bb4a4be299fbe58033ab7980' 
  AND token = 'eWJOE0hL+RZKXxccLl+rVnslWFPiOoNFXV9UPT06tBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}