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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd45f5bd519cb297c67c464b4a81d330176c919de2bcf2e8b8ced1b2d54efae50' 
  AND token = 'sA/oB0D3qFsNxQp9406p/QRA9P0zF2SNdAg5pmzmzro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}