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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '762c229f8f2827b77b1232f5cd9d8d25275ebb9e2994b719899fc99ec3b1a9b2' 
  AND token = '4tEkkMYdn18XoVQ4U7gvIRCXzHeAsKNuBLEvxcRLTzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}