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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c6ba645d77a000b35d5489c2be035a12a11020b2a8f802b7c8c6c4da1791a9b' 
  AND token = 'CxXmwF4mUKBOEiIoChMmiOjLNio7nx3pwXZg/nX6054=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}